ΑΝΕΠΑΡΚΕΙΑ
lichen planus
- the more the chronic and the more diffuse and sever LP was, the more the decrease in selenium level was seen
http://www.iraqijms.net/upload/pdf/iraqijms571725fc37582.pdf
ΑΝΤΙΜΕΤΩΠΙΣΗ (μερική, όχι πλήρη βελτίωση): 1 κλινική δοκιμή alone + 1 μαζί με ACE
oral lichen planus (32+30=62)
- 2020
aim of this clinical trial was to evaluate two Se forms (novel topical hydrogel and oral capsules), solely, in treating erosive OLP.
32 Patients were allocated into one of three groups:
group I, topical corticosteroids;
group II, topical Se; and
group III, systemic Se.
Treatment lasted for 6 weeks; patients were clinically evaluated at baseline, 6, and 12 weeks.
There was a significant reduction in signs and symptoms in response to all treatment modalities. However, there was no significant difference among the three groups at 6 weeks.
Selenium can be proposed as a treatment for OLP.
Qataya PO, Elsayed NM, Elguindy NM, Ahmed Hafiz M, Samy WM. Selenium: A sole treatment for erosive oral lichen planus (Randomized controlled clinical trial). Oral Dis. 2020 May;26(4):789-804. doi: 10.1111/odi.13285. Epub 2020 Feb 10. PMID: 31975475.
https://pubmed.ncbi.nlm.nih.gov/31975475/
https://www.researchgate.net/publication/338793860_Selenium_A_sole_treatment_for_erosive_oral_lichen_planus_Randomized-Controlled_Clinical_trial
2015
to evaluate the effect of selenium combined with Vitamins A, C & E (Selenium-ACE) in the treatment of erosive-ulcerative OLP as an adjunctive to topical corticosteroids plus antifungal agent.
30 patients were randomly allocated into one of three groups and treated as follows:
(I) Topical corticosteroids,
(II) topical corticosteroids plus antifungal, and
(III) SE-ACE combined with topical corticosteroids plus antifungal.
The patients were followed for 6 weeks.
Results: The experimental groups showed a marked reduction in pain sensation and size of lesions, but there was no significant difference between the first two Groups I and II. However, healing of lesions and improvement of pain sensation was effective in Group III since a significant difference was found favoring Group III over both Groups I and II.
The nutritional performance of each element in SE-ACE reaches its peak effectiveness when used in combination. Taking SE-ACE in a regular course, once daily every morning on an empty stomach
https://europepmc.org/article/MED/26681847
lichen planus
- the more the chronic and the more diffuse and sever LP was, the more the decrease in selenium level was seen
http://www.iraqijms.net/upload/pdf/iraqijms571725fc37582.pdf
ΑΝΤΙΜΕΤΩΠΙΣΗ (μερική, όχι πλήρη βελτίωση): 1 κλινική δοκιμή alone + 1 μαζί με ACE
oral lichen planus (32+30=62)
- 2020
aim of this clinical trial was to evaluate two Se forms (novel topical hydrogel and oral capsules), solely, in treating erosive OLP.
32 Patients were allocated into one of three groups:
group I, topical corticosteroids;
group II, topical Se; and
group III, systemic Se.
Treatment lasted for 6 weeks; patients were clinically evaluated at baseline, 6, and 12 weeks.
There was a significant reduction in signs and symptoms in response to all treatment modalities. However, there was no significant difference among the three groups at 6 weeks.
Selenium can be proposed as a treatment for OLP.
Qataya PO, Elsayed NM, Elguindy NM, Ahmed Hafiz M, Samy WM. Selenium: A sole treatment for erosive oral lichen planus (Randomized controlled clinical trial). Oral Dis. 2020 May;26(4):789-804. doi: 10.1111/odi.13285. Epub 2020 Feb 10. PMID: 31975475.
https://pubmed.ncbi.nlm.nih.gov/31975475/
https://www.researchgate.net/publication/338793860_Selenium_A_sole_treatment_for_erosive_oral_lichen_planus_Randomized-Controlled_Clinical_trial
2015
to evaluate the effect of selenium combined with Vitamins A, C & E (Selenium-ACE) in the treatment of erosive-ulcerative OLP as an adjunctive to topical corticosteroids plus antifungal agent.
30 patients were randomly allocated into one of three groups and treated as follows:
(I) Topical corticosteroids,
(II) topical corticosteroids plus antifungal, and
(III) SE-ACE combined with topical corticosteroids plus antifungal.
The patients were followed for 6 weeks.
Results: The experimental groups showed a marked reduction in pain sensation and size of lesions, but there was no significant difference between the first two Groups I and II. However, healing of lesions and improvement of pain sensation was effective in Group III since a significant difference was found favoring Group III over both Groups I and II.
The nutritional performance of each element in SE-ACE reaches its peak effectiveness when used in combination. Taking SE-ACE in a regular course, once daily every morning on an empty stomach
https://europepmc.org/article/MED/26681847
