ΑΝΕΠΑΡΚΕΙΑ (4)
oral lichen planus
1. 2001
25 patients with oral lichen planus.
The results revealed low red cell folate levels in 11 out of 25 patients (44%).
They were defined as having folate deficiency (n = 10), folate deficient erythropoiesis (n = 3) and folate depletion (n = 7).
Therefore, folate levels should be investigated in patients with oral lesions and symptoms especially those with risk factors of age, poor nutrition or systemic diseases. When suspected, daily folic acid supplements should be given.
Thongprasom K, Youngnak P, Aneksuk V. Folate and vitamin B12 levels in patients with oral lichen planus, stomatitis or glossitis. Southeast Asian J Trop Med Public Health. 2001 Sep;32(3):643-7. PMID: 11944731.
https://pubmed.ncbi.nlm.nih.gov/11944731/
https://www.researchgate.net/publication/11421352_Folate_and_vitamin_B12_levels_in_patients_with_oral_lichen_planus_stomatitis_or_glossitis
2. 2013
- 64 subjects (32 patients with OLP and 32 healthy samples)
the serum levels for Folic Acid was significantly lower in patients with OLP compared to healthy subjects. (p=0.03).
healthy subjects was 12.4±4.2 ng / ml whereas in patients with OLP it was found to be 9.45±4 ng / ml.
Nosratzehi T, Ansari moghaddam A, Arbabi-Kalati F, Maleki L, Amiriyan A. Effect of the Serum Vitamin B12 and Folic Acid levels in Oral Lichen Planus. J Res Dent Sci 2013; 9 (4) :187-191
http://jrds.ir/article-1-316-en.html
3. 2017
- 110 patients with LP (cutaneous and oral)
There were significantly higher prevalence of lower folic acid levels among patients' groups.
lower folic acid have been found in OLP when compared to CLP.
Rashed L, Abdel Hay R, AlKaffas M, Ali S, Kadry D, Abdallah S. Studying the association between methylenetetrahydrofolate reductase (MTHFR) 677 gene polymorphism, cardiovascular risk and lichen planus. J Oral Pathol Med. 2017 Nov;46(10):1023-1029. doi: 10.1111/jop.12588. Epub 2017 May 25. PMID: 28463405.
https://pubmed.ncbi.nlm.nih.gov/28463405/
4. 2018
EOLP patients did have significantly lower folic acid levels
Chang, J. Y. F., Wang, Y. P., Wu, Y. H., Su, Y. X., Tu, Y. K., & Sun, A. (2018). Hematinic deficiencies and anemia statuses in anti-gastric parietal cell antibody-positive or all autoantibodies-negative erosive oral lichen planus patients. Journal of the Formosan Medical Association, 117(3), 227–234. https://doi.org/10.1016/j.jfma.2017.12.009
https://www.mendeley.com/catalogue/993f7349-4eb8-3811-b340-20a73e02f258/
oral lichen planus
1. 2001
25 patients with oral lichen planus.
The results revealed low red cell folate levels in 11 out of 25 patients (44%).
They were defined as having folate deficiency (n = 10), folate deficient erythropoiesis (n = 3) and folate depletion (n = 7).
Therefore, folate levels should be investigated in patients with oral lesions and symptoms especially those with risk factors of age, poor nutrition or systemic diseases. When suspected, daily folic acid supplements should be given.
Thongprasom K, Youngnak P, Aneksuk V. Folate and vitamin B12 levels in patients with oral lichen planus, stomatitis or glossitis. Southeast Asian J Trop Med Public Health. 2001 Sep;32(3):643-7. PMID: 11944731.
https://pubmed.ncbi.nlm.nih.gov/11944731/
https://www.researchgate.net/publication/11421352_Folate_and_vitamin_B12_levels_in_patients_with_oral_lichen_planus_stomatitis_or_glossitis
2. 2013
- 64 subjects (32 patients with OLP and 32 healthy samples)
the serum levels for Folic Acid was significantly lower in patients with OLP compared to healthy subjects. (p=0.03).
healthy subjects was 12.4±4.2 ng / ml whereas in patients with OLP it was found to be 9.45±4 ng / ml.
Nosratzehi T, Ansari moghaddam A, Arbabi-Kalati F, Maleki L, Amiriyan A. Effect of the Serum Vitamin B12 and Folic Acid levels in Oral Lichen Planus. J Res Dent Sci 2013; 9 (4) :187-191
http://jrds.ir/article-1-316-en.html
3. 2017
- 110 patients with LP (cutaneous and oral)
There were significantly higher prevalence of lower folic acid levels among patients' groups.
lower folic acid have been found in OLP when compared to CLP.
Rashed L, Abdel Hay R, AlKaffas M, Ali S, Kadry D, Abdallah S. Studying the association between methylenetetrahydrofolate reductase (MTHFR) 677 gene polymorphism, cardiovascular risk and lichen planus. J Oral Pathol Med. 2017 Nov;46(10):1023-1029. doi: 10.1111/jop.12588. Epub 2017 May 25. PMID: 28463405.
https://pubmed.ncbi.nlm.nih.gov/28463405/
4. 2018
EOLP patients did have significantly lower folic acid levels
Chang, J. Y. F., Wang, Y. P., Wu, Y. H., Su, Y. X., Tu, Y. K., & Sun, A. (2018). Hematinic deficiencies and anemia statuses in anti-gastric parietal cell antibody-positive or all autoantibodies-negative erosive oral lichen planus patients. Journal of the Formosan Medical Association, 117(3), 227–234. https://doi.org/10.1016/j.jfma.2017.12.009
https://www.mendeley.com/catalogue/993f7349-4eb8-3811-b340-20a73e02f258/
